Researchers Documented Rare Neck HPV Case
A New York man sought medical care in 2025 for a clustered growth on his neck caused by HPV types 6 and 11.
Updated on Sept. 21, 2026 in Sexual Health
In 2025, medical professionals identified a case of extragenital HPV condylomas on the neck of a heterosexual man in his 40s. The patient, who had no history of other common sexually transmitted infections, presented with six verrucous brown papules.
Why it matters
While HPV types 6 and 11 are commonly associated with anogenital warts, identifying these strains in extragenital lesions helps clinicians recognize atypical clinical presentations. Understanding these rare cases improves diagnostic accuracy for dermatological growths.
The patient presented with six neck papules and an antinuclear antibody titer of 1:80, which exceeds the 1:40 reference limit. These lesions were identified as HPV 6 and 11, strains that typically account for 90% of anogenital warts.
The details
Medical staff treated the patient with cryotherapy, but the growth recurred after 11 months, requiring a follow-up shave biopsy. Testing for HIV, syphilis, chlamydia, and gonorrhea was negative, and the biopsy confirmed papillated epidermal hyperplasia.
Timeline
The patient first noticed the growth on his neck in 2024.
The patient sought medical treatment for the neck growth in 2025.
The patient returned for recurrence 11 months after the initial treatment in 2026.
The Big Picture
This case study aligns with established dermatological surveillance protocols by expanding the clinical documentation of rare HPV manifestations. The findings follow the trends in pathology research, providing updated figure comparisons for clinicians managing non-genital HPV presentations.
This case highlights the importance of biopsy for recurring skin lesions that do not respond to initial cryotherapy treatments. Patients with persistent or clustered neck growths should consult a dermatologist to rule out viral causes, even in the absence of other symptoms.
The takeaway
This case demonstrates that HPV types 6 and 11 can present as extragenital lesions even in immunocompetent individuals. Regular dermatological screening is recommended for any persistent or recurring skin growths on the neck or other areas.
Further reading
For more information on the evolving understanding of virus transmission and skin health, visit Sexual Health.
Source note: This article includes information reported by Cdc.
