mRNA Flu Vaccines Arrived in Des Moines
New mRNA-based influenza shots are now available at local CVS pharmacies and Costco locations.
Updated on Oct. 13, 2026 in Allergies

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The mRNA flu vaccine has been released to pharmacy shelves across Des Moines. The vaccine offers an alternative to traditional flu shots for local residents.
Why it matters
The mRNA vaccine provides a more effective option for flu prevention compared to standard shots. This development aims to improve public health outcomes during the active flu season.
The mRNA flu vaccine showed a 27% risk reduction versus standard shots in a trial of 40,000 adults. Positive flu tests hit 3.6% in early October, compared to 0.6% during the same period last year.
The players
CVS
A national retail pharmacy chain that provides prescription medications and health services.
Costco
An international membership-based wholesale corporation that operates retail pharmacies.
The details
The vaccine is now accessible at CVS pharmacies and Costco throughout the Des Moines area. Clinical trials documented that side effects, such as injection site pain, fatigue, and headaches, were categorized as mild.
Timeline
Last flu season saw 34% of Polk County residents receive a flu shot.
Early October 2026 recorded a 3.6% positive flu test rate.
Health Landscape
The deployment of this vaccine follows the widespread implementation of the mRNA technology platforms utilized in COVID-19 vaccinations. This shift marks a transition in seasonal preventative care by applying proven mRNA methods to combat influenza.
Residents can now choose between the new mRNA option and standard shots at local providers. Those who receive the vaccine should be prepared for potential mild side effects such as fatigue or a headache following the injection.
The takeaway
The arrival of mRNA-based flu vaccines offers a new tool for local residents to reduce their risk of infection this season. Patients should consult their pharmacist to discuss which vaccination option is most appropriate for their health needs.
Further reading
For more information on seasonal health trends, visit Allergies.
Source note: This article includes information reported by Axios.
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