Matthew Stafford Set NFL Career Pick-Six Record
Stafford reached 33 career pick-sixes after an interception by Talanoa Hufanga in a game against the Denver Broncos.
Updated on Sept. 28, 2026 in Football

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Matthew Stafford has set the NFL all-time record for career interceptions returned for touchdowns following a pick-six in the fourth quarter. The pivotal play occurred during a game against the Denver Broncos in Denver.
Why it matters
The milestone marks a significant shift in the record books for one of the most prolific passers in league history. The turnover proved decisive, erasing a Rams lead and placing the Broncos in front by four points.
Stafford now holds the NFL all-time record with 33 career interceptions returned for touchdowns. This figure surpasses the previous record of 32 held by Brett Favre, while Dan Marino remains third on the all-time list with 29.
The players
Matthew Stafford
He is an veteran NFL quarterback who has played for the Detroit Lions and the Los Angeles Rams.
Talanoa Hufanga
He is a professional football player who recorded the game-changing interception against Stafford.
Brett Favre
He is a retired Pro Football Hall of Fame quarterback who previously held the record for career pick-sixes.
Dan Marino
He is a legendary former NFL quarterback who ranks third all-time in career interceptions returned for touchdowns.
The details
Late in the fourth quarter, Stafford threw an interception to Talanoa Hufanga, who returned the ball for a touchdown. The scoring play turned a three-point Rams advantage into a four-point lead for the Broncos.
Timeline
September 27, 2026, was the date of the game between the Los Angeles Rams and the Denver Broncos.
Season Trajectory
This record-setting moment forces a reevaluation of the Rams' offensive stability as they navigate a competitive season. The turnover highlights the high-risk nature of the passing attack and its direct impact on the team's ability to maintain leads in tight games.
The pick-six immediately altered the game's momentum, shifting the score by a seven-point swing. Fantasy managers and fans should note the impact of this turnover on the team's overall offensive efficiency.
The takeaway
Stafford's new record highlights the extreme risks associated with aggressive quarterback play over an extended career. Even elite signal-callers can accumulate high turnover numbers that significantly alter game outcomes.
Further reading
For more news from the league, visit our Football section.
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