Nick Bosa Missed 49ers Game Against Broncos

The San Francisco 49ers defensive star remained sidelined this week while nursing a calf injury.

Updated on Oct. 4, 2026 in Football

Expressive sports illustration of a football player in 49ers colors, capturing the tension of game day without specific athlete identification. — San Francisco 49ers defensive end Nick Bosa missed his second consecutive game on Sunday while recovering from a calf injury. AI Illustration. Upload story photo >

Nick Bosa has missed his second consecutive game as he continues to recover from a calf injury. The defensive end was unavailable for the San Francisco 49ers during their matchup against the Denver Broncos.

Why it matters

Bosa remains a key component of the team defense, and his prolonged absence impacts the 49ers on-field performance. He is not currently expected to miss significant additional time due to the injury.

Nick Bosa has been ruled out for two straight games following a calf injury. This period of absence follows a season in 2025 where the player previously dealt with a torn ACL.

The players

Nick Bosa

He is a defensive end for the San Francisco 49ers who has been a central figure in the team defense.

Ella Ailiff

She is a public figure who has been in a relationship with Nick Bosa since late 2025.

The details

The defensive standout, who has been linked to Ella Ailiff since late 2025, has focused on rehabilitation while his team faced Denver. Ailiff recently highlighted her support for the team by sharing images of herself wearing 49ers attire.

Nick Bosa and Ella Ailiff went official with their relationship in 2025.
Ailiff watched Bosa play against the Dolphins during Week 2 of 2026.
This report was published on October 4, 2026.

Season Trajectory

Bosa's absence directly impacts the defensive rotation and pass-rush effectiveness for the 49ers during a critical stretch of the season. His return is vital for maintaining the team standing in the division as they aim to stabilize their defensive front.

The absence of Bosa forces the 49ers defensive scheme to adjust, which may provide more opportunities for opposing offensive lines to neutralize the pass rush. Fantasy managers should prepare for potential impacts to the team total defensive scoring output while he remains out of the lineup.

The takeaway

Maintaining player health throughout the season is essential for long-term team success. Fans should monitor official injury reports for updates regarding Bosa and his return to the field.