CDC Lost One Third of Its Workforce
The agency experienced massive staff attrition and unit eliminations between March 2025 and April 2026.
Updated on Sept. 26, 2026 in COVID-19

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The Centers for Disease Control and Prevention saw its total workforce drop by one third between March 2025 and April 2026. This period of significant attrition followed a series of structural agency changes.
Why it matters
The staff reductions led to organizational gaps, including the lack of formal recommendations for the 2026 flu vaccine despite its approval by the FDA. The depletion of personnel, particularly in critical administrative roles, has halted standard advisory operations.
Agency staffing dropped by one third in the 13-month period, while 100 percent of staff were lost at two eliminated units. This reduction occurred as 98 percent of human resources personnel left the agency.
The players
Centers for Disease Control and Prevention
This is the primary federal agency responsible for protecting public health and safety in the United States.
Department of Government Efficiency
This entity was responsible for implementing staff and unit reductions at federal agencies starting in 2025.
Demetre Daskalakis
He served as a high-ranking official at the CDC before resigning during the summer of 2025.
The details
The Department of Government Efficiency initiated the removal of agency units in spring 2025, leading to the elimination of the Office of Health Equity and the Office of Equal Employment Opportunity. Following these initial cuts, remaining employees left the agency through voluntary departures and retirements.
Timeline
March 2025: The CDC workforce attrition period began.
Spring 2025: The Department of Government Efficiency eliminated agency units.
Summer 2025: Demetre Daskalakis resigned.
April 2026: The CDC workforce attrition period concluded.
August 2026: The FDA approved a new flu vaccine.
Health Landscape
The CDC's federal public health advisory infrastructure is currently undergoing a massive reorganization of its labor force. This period marks a significant departure from the established operational capacity of this institution.
The lack of official CDC guidance on the 2026 flu vaccine complicates seasonal health decisions for the public. Patients should consult their personal healthcare providers directly for vaccination advice in the absence of federal recommendations.
The takeaway
The drastic reduction in specialized staff has created a void in the federal health advisory ecosystem. Citizens should rely on local public health departments or private physicians to fill the information gap created by the agency's diminished capacity.
Further reading
For additional context on agency health guidelines, visit COVID-19.
Source note: This article includes information reported by Mother Jones.
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