CDC Lost One Third of Its Workforce

The agency experienced massive staff attrition and unit eliminations between March 2025 and April 2026.

Updated on Sept. 26, 2026 in COVID-19

Isometric editorial illustration showing a sparse, empty administrative floor with rows of vacant workstations, representing federal institutional staffing declines.
The CDC's total workforce decreased by one-third between March 2025 and April 2026, creating critical gaps in agency operations and administrative oversight. AI Illustration. Upload story photo >

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The Centers for Disease Control and Prevention saw its total workforce drop by one third between March 2025 and April 2026. This period of significant attrition followed a series of structural agency changes.

Why it matters

The staff reductions led to organizational gaps, including the lack of formal recommendations for the 2026 flu vaccine despite its approval by the FDA. The depletion of personnel, particularly in critical administrative roles, has halted standard advisory operations.

Agency staffing dropped by one third in the 13-month period, while 100 percent of staff were lost at two eliminated units. This reduction occurred as 98 percent of human resources personnel left the agency.

The players

Centers for Disease Control and Prevention

This is the primary federal agency responsible for protecting public health and safety in the United States.

Department of Government Efficiency

This entity was responsible for implementing staff and unit reductions at federal agencies starting in 2025.

Demetre Daskalakis

He served as a high-ranking official at the CDC before resigning during the summer of 2025.

The details

The Department of Government Efficiency initiated the removal of agency units in spring 2025, leading to the elimination of the Office of Health Equity and the Office of Equal Employment Opportunity. Following these initial cuts, remaining employees left the agency through voluntary departures and retirements.

Timeline

  1. March 2025: The CDC workforce attrition period began.

  2. Spring 2025: The Department of Government Efficiency eliminated agency units.

  3. Summer 2025: Demetre Daskalakis resigned.

  4. April 2026: The CDC workforce attrition period concluded.

  5. August 2026: The FDA approved a new flu vaccine.

Health Landscape

The CDC's federal public health advisory infrastructure is currently undergoing a massive reorganization of its labor force. This period marks a significant departure from the established operational capacity of this institution.

The lack of official CDC guidance on the 2026 flu vaccine complicates seasonal health decisions for the public. Patients should consult their personal healthcare providers directly for vaccination advice in the absence of federal recommendations.

The takeaway

The drastic reduction in specialized staff has created a void in the federal health advisory ecosystem. Citizens should rely on local public health departments or private physicians to fill the information gap created by the agency's diminished capacity.

Further reading

For additional context on agency health guidelines, visit COVID-19.

Source note: This article includes information reported by Mother Jones.

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Should the federal government prioritize maintaining high staffing levels at public health agencies?