Promega Corporation Released DNA Analysis System
The new system utilizes engineered enzymes to enhance accuracy in forensic DNA identification and contributor analysis.
Updated on Sept. 29, 2026 in Biotech
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Promega Corporation has launched the Paradyme 27GY STR System, a new technology designed for improved forensic DNA analysis. This system uses a proprietary enzyme to significantly reduce stutter signals in complex samples.
Why it matters
By reducing stutter signal intensity, the system allows forensic analysts to more accurately determine the number of contributors in mixed DNA samples. This advancement enhances the ability to detect minor contributors within degraded biological evidence.
The system features a 23-autosomal STR loci configuration and utilizes an 8-dye multiplex designed for degraded sample amplification. The proprietary Reduced-Stutter Polymerase minimizes slippage during the amplification of repetitive DNA sequences.
The players
Promega Corporation
Based in Madison, Wisconsin, this company has provided life science research tools and forensic analysis technology for 45 years.
The details
Developed in Madison, the Paradyme 27GY STR System integrates with the company’s existing Spectrum CE and Spectrum Compact CE platforms. It provides a technical framework for analyzing Amelogenin and Y-STR loci alongside its 23 autosomal markers.
Timeline
Promega initially unveiled the engineered enzyme at a symposium in 2024.
The Paradyme 27GY STR System was officially launched on September 29, 2026.
The Tech Race
The introduction of the Paradyme 27GY STR System represents the latest evolution in the high-stakes sector of forensic biotechnology. It moves beyond standard amplification methods to compete for market share in laboratories requiring high-resolution DNA contributor determination.
Forensic labs utilizing this technology may experience faster and more reliable processing of complex DNA evidence. This potentially reduces the turnaround time for analysis in criminal investigations where mixed biological samples are common.
The takeaway
The implementation of reduced-stutter enzymes signals a major shift toward higher confidence levels in forensic evidence interpretation. Crime labs can use this technical precision to better identify individuals from challenging, low-template DNA mixtures.
Further reading
Learn more about the latest innovations in Biotech.
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