Veterinary Researchers Tested Histotripsy on Horse Tumor
A team in Virginia used focused ultrasound technology to non-invasively remove a sarcoid from a nine-year-old mare.
Updated on Sept. 27, 2026 in Veterinary Medicine
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In spring 2026, researchers at the Virginia-Maryland College of Veterinary Medicine successfully used histotripsy to destroy a sarcoid tumor on a horse. The non-invasive treatment utilized focused ultrasound waves to eliminate the growth during a single overnight stay.
Why it matters
Traditional sarcoid treatments often involve invasive surgery or chemotherapy, which can complicate long-term recovery for horses. This method aims to offer a less painful, non-invasive alternative to prevent recurring management issues or potential euthanasia.
The procedure involved a nine-year-old Hanoverian mare that remained standing and sedated during the treatment. Histotripsy uses focused ultrasound waves to create microscopic bubble clouds that collapse to destroy targeted tumor tissue.
The players
Virginia-Maryland College of Veterinary Medicine
This institution is a joint venture between Virginia Tech and the University of Maryland focused on veterinary research and clinical practice.
The details
The treatment process involved applying a wearable device to deliver focused ultrasound waves that mechanically broke down the cancer cells. This research builds upon previous successful applications of the technology for treating canine cancer and human lab-based tumor studies.
Timeline
The histotripsy system received its first live test in spring 2026.
Roadmap
This study follows a pattern set by the existing histotripsy research program for canine cancer treatment. Researchers now aim to scale this technology into a portable device that could eventually become a standard tool for veterinary practices nationwide.
Horse owners may eventually benefit from a less invasive option for common skin tumors that avoids the risks of surgery or chemotherapy. The development of a portable device could lead to more accessible, office-based tumor removal services for equine patients in the future.
The takeaway
Histotripsy represents a shift toward mechanical rather than chemical tumor destruction in veterinary oncology. This technology shows potential for treating various skin conditions without the need for extensive recovery periods.
Further reading
Learn more about the latest developments in animal care and research at Veterinary Medicine.
Source note: This article includes information reported by Horse & Hound.
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