Sanford Health Builds New Clinic in Southeast Sioux Falls

The medical facility at 57th Street and Veterans Parkway aims to serve the rapidly expanding southeast corner of the city.

Updated on Oct. 27, 2026 in Openings & Closings

Steel frame of an unfinished building rising from a suburban construction site under a clear blue sky.
Sanford Health began construction in October 2026 on a new medical facility at 57th Street and Veterans Parkway to serve southeast Sioux Falls. AI Illustration. Upload story photo >

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Sanford Health began construction in October 2026 on a new medical clinic located at 57th Street and Veterans Parkway in Sioux Falls. The facility will feature an attached Lewis Drug store to provide integrated pharmacy services to the community.

Why it matters

The project addresses the rapid population growth in the southeast corner of Sioux Falls, ensuring residents have localized access to essential healthcare services.

The new facility includes 34 exam rooms and five treatment rooms to support its diverse clinical departments. The site offers a variety of services ranging from pediatrics to gynecology and walk-in labs.

The players

Sanford Health

Sanford Health is a major non-profit integrated health system headquartered in Sioux Falls that operates numerous hospitals and clinics across the upper Midwest.

Lewis Drug

Lewis Drug is a prominent regional pharmacy and retail chain that often partners with local health providers to locate stores within or adjacent to medical facilities.

The details

The facility provides a wide range of services including acute care, family medicine, pediatrics, and gynecology, alongside radiology and therapy. A Lewis Drug store is being constructed as an attached retail component of the clinic building.

Timeline

  1. Construction on the facility began in October 2026.

  2. The clinic is expected to open in August 2028.

Market Landscape

This development follows a pattern set by regional healthcare providers to expand services into newly developed residential areas of the city. By attaching retail pharmacy space to the clinic, Sanford Health is capitalizing on the trend of integrating medical and retail services for convenience.

Residents in the southeast corner of the city will gain access to walk-in labs, therapy, and family medicine close to home by 2028. The inclusion of an attached Lewis Drug store will streamline the process of filling prescriptions immediately after clinic appointments.

The takeaway

The addition of this facility reflects the ongoing urban development needs of the southeast Sioux Falls area. Local residents should track the progress of the site as the projected August 2028 opening date approaches.

Further reading

Find more local business updates in the Sioux Falls Openings & Closings section.

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Is healthcare access in your community becoming more convenient for residents?