North Carolina Awarded Small Business Biotech Grants

The state distributed over $2.4 million in fiscal year 2026 to support local tech innovation and business growth.

Updated on Sept. 28, 2026 in Biotech

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The North Carolina Department of Commerce distributed $2.4 million in fiscal year 2026 to 46 small businesses to advance local biotechnology innovation. AI Illustration. Upload story photo >

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Should states provide matching grant funding to local small technology businesses?

In fiscal year 2026, the North Carolina Department of Commerce awarded 50 grants to 46 small businesses across 13 counties. The funding initiative, which helps companies bridge the gap between initial concept and sustainable revenue, totaled over $2.4 million.

Why it matters

These grants provide critical financial support to companies developing innovative technologies by supplementing federal funding. The program plays a key role in helping early-stage businesses commercialize their products and sustain operations.

The state awarded 32 Matching grants totaling $2,368,506.63 and 18 Incentive grants worth $116,553.37. Additionally, six companies in Hurricane Helene-impacted counties received $313,888.52 in total, including $25,000 supplemental awards.

The players

North Carolina Department of Commerce

This is the state agency responsible for overseeing economic development and managing the distribution of small business grants.

Deep Creek Pharma

This is a biotech company based in Yadkinville, North Carolina, that focuses on the development of oncology treatments.

The details

Deep Creek Pharma, located in Yadkinville, received a $100,000 grant to assist in the development of its oncology treatments. The program assists firms that have already secured awards from federal Small Business Innovation Research and Small Business Technology Transfer initiatives.

Timeline

  1. The One North Carolina Small Business Program began its operations in 2006.

  2. The state fiscal year 2026 concluded on June 30, 2026.

The Tech Race

This program aligns with federal efforts to accelerate the commercialization of high-tech research by bridging the funding gap for small innovators. By leveraging state capital to supplement federal grants, North Carolina maintains a competitive edge in attracting and retaining biotech firms.

Local small businesses benefit from these awards through increased capacity to fund research and development, potentially leading to new biotech job opportunities. Residents in hurricane-impacted areas also receive targeted financial support to maintain business continuity during recovery.

The takeaway

Small businesses in highly technical fields often rely on a combination of federal and state support to navigate the expensive development phase of new technologies. Entrepreneurs should monitor state-level grant windows to leverage existing federal awards for additional operational funding.

Further reading

Learn more about the state's efforts to support local innovation in our Biotech section.

Source note: This article includes information reported by Yadkin Ripple.

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Should states provide matching grant funding to local small technology businesses?