Mayo Clinic Names Dr. Matthew Callstrom Next CEO
The Mayo Clinic Board of Trustees chose Dr. Matthew Callstrom to succeed Dr. Gianrico Farrugia as president and CEO.
Updated on Nov. 13, 2026 in People
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The Mayo Clinic Board of Trustees selected Dr. Matthew Callstrom as the institution's next president and CEO, announced Friday. Dr. Gianrico Farrugia, who has led Mayo Clinic since January 2019, will step down effective January 1, 2027.
Why it matters
The appointment sets the leadership for one of Rochester's largest institutions as Mayo Clinic continues integrating artificial intelligence into medical practice. Callstrom's internal experience at the clinic signals continuity in its strategic direction.
Callstrom has nearly 25 years of Mayo Clinic experience, dating to his 2002 arrival, while Farrugia's tenure as president and CEO began in January 2019. The stub does not specify the financial or operational metrics Callstrom will oversee.
The players
Mayo Clinic
Mayo Clinic is a nonprofit academic medical center headquartered in Rochester, Minnesota, known for its integrated clinical care, research and medical education.
Dr. Matthew Callstrom
Dr. Matthew Callstrom is a physician-scientist and radiologist who has spent nearly 25 years at Mayo Clinic and helped lead its integration of AI into medical practice.
Dr. Gianrico Farrugia
Dr. Gianrico Farrugia has led Mayo Clinic as president and CEO since January 2019 and is stepping down at the end of 2026.
The details
Callstrom, a physician-scientist and radiologist, is a Minnesota native who serves on the Board of Governors and Board of Trustees. He currently serves as medical director for the Mayo Clinic Strategy and AI Program and previously served as interim chief strategy officer and chair of the Radiology Department.
Timeline
January 2019: Farrugia began serving as Mayo Clinic president and CEO.
2002: Callstrom joined Mayo Clinic.
November 13, 2026: The Board of Trustees selected Callstrom as next president and CEO.
December 31, 2026: Farrugia's tenure as president and CEO ends.
January 1, 2027: Callstrom assumes the role of president and CEO.
Market Landscape
Callstrom's background running Mayo Clinic's Strategy and AI Program positions him to steer the institution's AI integration at the executive level. The succession extends a leadership path that moves internal strategy and radiology expertise into the top role.
For patients and staff, the leadership transition is a scheduled handoff with no change in effect until January 1, 2027. The stub does not describe changes to services, pricing or access.
The takeaway
Leadership successions at major medical institutions are typically planned well in advance, and Mayo Clinic's timeline gives the public a year-plus window before the change takes effect.
What happens next
Dr. Gianrico Farrugia's tenure as president and CEO ends December 31, 2026, and Dr. Matthew Callstrom assumes the role January 1, 2027.
Further reading
Explore more People coverage in the Rochester business section.
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