Naples Hospital Performs First Liberant Clot Procedure

Naples Comprehensive Health has performed its first case using Medtronic's Liberant Thrombectomy System to remove certain blood clots.

Updated on Nov. 9, 2026 in Stroke

Coiled catheter tube resting on a stainless steel tray beside a pale blue sterile drape in a bright, clean medical room.
Naples Comprehensive Health has performed its first case using Medtronic's Liberant Thrombectomy System to remove certain blood clots. AI Illustration. Upload story photo >

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Naples Comprehensive Health performed its first case using Medtronic's Liberant Thrombectomy System, a catheter-based procedure for removing certain blood clots. The hospital also became the first in Florida to use Medtronic's Excipio device.

Why it matters

Venous thromboembolism affects an estimated 900,000 people in the United States each year, and the Liberant system offers a catheter-based alternative to overnight clot-buster infusions for serious clots. Local patients in Naples may gain access to a procedure that could shorten hospital stays.

The CDC estimates up to 900,000 Americans are affected by venous thromboembolism each year, and the procedure takes about 30 to 40 minutes. Patient outcomes from the hospital's initial case have not been reported.

The players

Medtronic

Medtronic is a global medical technology company that develops devices including the Liberant Thrombectomy System and Excipio.

Naples Comprehensive Health

Naples Comprehensive Health is a hospital in Naples, Florida that performed the first Liberant procedure.

The details

The Liberant system removes fresh, soft clots from peripheral arteries and veins by combining a mechanical component that scrapes off part of the clot with a suction catheter. Access is usually through the groin or the back of the knee, and patients may be able to go home the following day.

Timeline

  1. June 2025: FDA cleared the Liberant system for removing fresh, soft clots from peripheral arteries and veins.

  2. Spring 2026: Naples Comprehensive Health performed its first Liberant case.

Roadmap

Catheter-based mechanical thrombectomy devices cleared by the FDA are replacing overnight catheter infusions of clot-buster medication for certain serious clots. The Liberant system, cleared in June 2025, extends that shift to fresh, soft clots in peripheral arteries and veins.

Patients with certain fresh, soft clots may be treated with a procedure lasting about 30 to 40 minutes rather than overnight infusions. Many patients may be able to return home the day after treatment.

The takeaway

Catheter-based clot removal may reduce reliance on overnight infusions for eligible patients. Anyone experiencing symptoms of a blood clot should seek prompt medical evaluation from a healthcare provider.

Further reading

Explore more on Stroke to see how clot removal fits into broader treatment options.

Source note: This article includes information reported by WBBH.

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Would you feel comfortable with a newer, faster catheter procedure for blood clots?