Chargers Released Week 3 Injury Report
Eight players sat out of Los Angeles practice on Wednesday ahead of the upcoming matchup against the Buffalo Bills.
Updated on Sept. 23, 2026 in Football

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The Los Angeles Chargers issued an injury report ahead of their Week 3 game against the Buffalo Bills. Eight players did not participate in the team's first practice of the week on Wednesday.
Why it matters
Managing player health and practice participation is critical for team depth as the Chargers prepare for the challenge of facing the Bills. These updates provide insight into lineup availability for the upcoming contest.
Eight players did not participate in Wednesday's session, including Charlie Kolar who recently underwent surgery. This total represents the number of players listed as non-participants on the team's first injury report of the week.
The players
Los Angeles Chargers
The Los Angeles Chargers are a professional football team competing in the National Football League.
Charlie Kolar
Charlie Kolar is a football player for the Los Angeles Chargers who recently underwent forearm surgery.
Derwin James
Derwin James is a standout defensive player for the Los Angeles Chargers currently dealing with a finger injury.
Khalil Mack
Khalil Mack is a veteran defensive star for the Los Angeles Chargers who was excused from practice for rest.
Buffalo Bills
The Buffalo Bills are a professional football team scheduled to face the Los Angeles Chargers in Week 3.
The details
The report includes various ailments ranging from hamstring and knee injuries to a finger issue for Derwin James. Charlie Kolar is confirmed to miss the game following his procedure, while Khalil Mack was absent for a rest day.
Timeline
Charlie Kolar underwent surgery on Monday.
The team conducted its first practice of the week on Wednesday.
Season Trajectory
This roster disruption forces the coaching staff to adjust their game plan during a pivotal early-season matchup. Managing these absences is essential to maintaining the team's competitive standing within the division.
Fantasy managers should monitor the status of Derwin James and other starters ahead of the final inactive list release. The absence of key players on defense may significantly alter the team's defensive rotation against Buffalo.
The takeaway
Maintaining depth across the roster is vital for navigating the physical demands of an NFL season. Fans can track progress toward game day by observing which players return to limited participation later in the week.
Further reading
For more updates on the team, visit the Los Angeles Football section.
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