Teddi Mellencamp Reflects on Cancer and Split

The Real Housewives star discussed her melanoma battle and the end of her relationship with PJ Conley on a podcast episode.

Updated on Nov. 4, 2026 in Cancer

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Reality TV star Teddi Mellencamp discussed her melanoma battle and the end of her relationship with PJ Conley on her podcast Two Ts In A Pod. AI Illustration. Upload story photo >

Teddi Mellencamp reflected on her cancer battle and her relationship split in a video posted to her Instagram Story on November 3, 2026. The video addressed the latest episode of her podcast, Two Ts In A Pod, where she said the end of her relationship with PJ Conley left her emotional.

Why it matters

Mellencamp said she became emotional because the breakup overlapped with fears about her future while living with cancer. Her account offers a personal look at the emotional toll of a serious diagnosis alongside a major life change.

Mellencamp was diagnosed with stage 2 melanoma in 2022 and said in April 2025 that it had spread to her brain and lungs. In August 2026 she disclosed nine months of cancer treatment remaining, and her current prognosis was not addressed in the reported statements.

The players

Teddi Mellencamp

Mellencamp is a reality television personality known for her time on The Real Housewives of Beverly Hills and a podcast co-host.

PJ Conley

Conley is the former boyfriend of Teddi Mellencamp whose relationship with her ended around the time of her podcast reflections.

The details

In her Instagram Story, Mellencamp discussed the latest episode of her podcast, Two Ts In A Pod, in which she described the end of her relationship with PJ Conley and her cancer-related fears. She said she had undergone several surgeries and continued regular immunotherapy after her initial diagnosis.

Timeline

  1. 2022: Mellencamp was initially diagnosed with stage 2 melanoma.

  2. April 2025: Her cancer was reported to have spread to her brain and lungs.

  3. August 2026: She revealed nine months of cancer treatment remained.

  4. November 3, 2026: She posted the video reflecting on her podcast episode.

Health Landscape

Mellencamp's continued immunotherapy after surgery reflects the standard approach for melanoma that has spread beyond its original site. Her public account highlights how patients with metastatic disease often face long treatment courses that shape their personal and emotional lives.

Immunotherapy can be an ongoing treatment for melanoma that has spread, requiring regular infusions over extended periods. Readers following similar diagnoses may want to ask their care teams about treatment schedules and monitoring.

The takeaway

Mellencamp's account shows that the emotional impact of cancer treatment can extend well beyond physical symptoms into relationships and future planning. Patients living with advanced disease often benefit from support networks that address both medical and personal needs.

Further reading

Learn more about treatment options in our Cancer coverage.