FDA Warns of Hidden Drugs in Arthritis Supplements

The FDA identified undisclosed pharmaceutical ingredients in the pain-relief products RX7 Articulaciones and Ort-Flx.

Updated on Oct. 31, 2026 in Arthritis

Amber dropper bottle and beaker of white powder on a clinical laboratory surface, indicating hidden ingredients in supplements. — The FDA warned consumers about RX7 Articulaciones and Ort-Flx after finding undisclosed prescription-level ingredients, including diclofenac and dexamethasone, in the supplements. AI Illustration. Upload story photo >

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The FDA recently issued warnings regarding the presence of undeclared drug ingredients in RX7 Articulaciones and Ort-Flx. Both products were found to contain the anti-inflammatory drug diclofenac and the corticosteroid dexamethasone, while Ort-Flx also contains the muscle relaxant methocarbamol.

Why it matters

The presence of these undisclosed chemicals can cause serious health consequences for unsuspecting users. The agency is advising consumers to consult a healthcare professional before stopping use, as suddenly ceasing intake of corticosteroids can trigger dangerous withdrawal symptoms.

FDA lab tests confirmed these supplements contain unlisted pharmaceuticals, joining a total of 22 such products identified since 2013. The agency utilizes its MedWatch program to track adverse reactions reported by the public.

The players

Food and Drug Administration

The federal agency responsible for protecting public health by ensuring the safety and efficacy of human drugs, biological products, and medical devices.

The details

Agency testing confirmed these over-the-counter products contain prescription-level substances not listed on their labels. While the products were sold on platforms such as eBay, the FDA has not issued a formal recall for the supplements at this time.

The FDA identified 22 arthritis and pain products with hidden ingredients between 2013 and 2023.
The agency issued warnings against similar Artri and Ortiga products in April 2022.
Official notices regarding RX7 Articulaciones and Ort-Flx were posted on October 28, 2026.

Health Landscape

This discovery highlights the ongoing challenges the FDA faces in regulating the supplement market under the protocols established by the MedWatch program. It serves as a reminder of the complexities involved in identifying hidden substances in products sold through diverse online marketplaces.

Consumers should not abruptly discontinue use of these supplements without first consulting a physician to avoid potential corticosteroid withdrawal. Anyone who has experienced adverse side effects is encouraged to report them to the agency via the MedWatch program.

The takeaway

Supplements sold through third-party online platforms can carry hidden pharmaceutical risks that are not disclosed on packaging labels. Always consult with a healthcare professional before adding new supplements to your routine, especially if managing chronic pain.