Joe Manganiello Reveals Details of 2016 Intestinal Surgery
The 49-year-old actor explains how an autoimmune condition necessitated emergency surgery and the use of an ostomy bag.
Updated on Oct. 24, 2026 in Weight Loss
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Joe Manganiello is opening up about a 2016 medical crisis that led to the removal of his large intestine. The actor navigated this health struggle while filming his role as Deathstroke in Justice League.
Why it matters
By sharing his experience, Manganiello aims to destigmatize the use of ostomy bags and encourage open dialogue about similar chronic health challenges.
Following his emergency surgery in 2016, Manganiello experienced a rapid weight loss of 60 pounds in two weeks. This procedure occurred after a seven-year struggle with an undiagnosed autoimmune condition.
The players
Joe Manganiello
He is a 49-year-old actor known for his roles in major film franchises and television series.
The details
Doctors performed the life-saving operation to remove his entire large intestine after extensive testing failed to pinpoint the cause of the actor's collapse. Manganiello notably wore an ostomy bag beneath his costume throughout the production of Justice League.
Timeline
In 2016, Joe Manganiello underwent emergency surgery to remove his large intestine.
On October 24, 2026, the actor publicly revealed his medical history on The Tonight Show.
Health Landscape
This disclosure follows the precedent set by other high-profile figures who have used their platform to demystify complex medical conditions. It marks a shift toward greater transparency regarding the physical realities of living with chronic autoimmune illnesses.
The actor's story serves as a reminder of the challenges patients face when managing long-term autoimmune conditions and post-surgical recovery. It highlights the importance of public awareness regarding the daily realities and medical necessities for those using ostomy bags.
The takeaway
Publicly discussing hidden medical struggles helps break down barriers for patients adjusting to life with medical devices. Implementing open communication about one's health can foster a more supportive environment for those managing chronic illnesses.
Further reading
For more information on managing chronic health conditions, visit the Weight Loss section.
Source note: This article includes information reported by NewKerala.
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