HPE Launches New ProLiant Gen13 Data Center Servers
The latest server line integrates 6th Generation AMD EPYC processors to power AI and large-scale simulation workloads.
Updated on Oct. 16, 2026 in Data Centers

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Hewlett Packard Enterprise has unveiled four new ProLiant Gen13 server models designed to support complex tasks like agentic AI, analytics, and simulation. The new systems leverage 6th Generation AMD EPYC processors to deliver enhanced core density and memory bandwidth for enterprise data centers.
Why it matters
These systems are designed to address the growing demand for reliable infrastructure to support high-performance AI and modeling workloads. By prioritizing advanced security and performance, the servers aim to meet the requirements of enterprises needing stability for mission-critical operations.
The new ProLiant Gen13 line includes the DL585a, which supports up to eight double-wide PCIe GPUs, and the DL525, which features a single socket with up to 256 cores. The hardware integrates security features such as post-quantum cryptography readiness and self-encrypting drive capabilities.
The players
Hewlett Packard Enterprise
This global information technology company provides servers, storage, and networking hardware solutions for enterprise data centers.
AMD
This multinational semiconductor company designs high-performance processors used in data center computing and consumer electronics.
The details
The ProLiant Gen13 servers incorporate HPE iLO 8 and Compute Ops Management to streamline server deployment and maintenance. The XD245 model features a four-node direct liquid-cooled design, while the XD285 provides a two-node air-cooled alternative to suit various data center thermal environments.
Timeline
The DL525 Gen13 server is scheduled for availability in 2026.
The DL585a Gen13 server is expected to reach the market in early 2027.
The XD245 and XD285 Gen13 servers are slated for release in 2027.
The Tech Race
The introduction of Gen13 servers reflects an industry-wide pivot toward specialized hardware optimized for agentic AI and massive data simulation. This move positions HPE to compete directly with rival server manufacturers that are racing to integrate the latest high-density processing architectures.
Enterprises utilizing these servers can expect streamlined deployment and reduced unplanned downtime, which historically reaches 97% reduction for users of HPE management tools. These efficiencies help organizations maintain better operational consistency when managing large-scale AI and virtualization workloads.
The takeaway
Enterprise operators should focus on hardware reliability when planning future AI and simulation deployments, as performance consistency remains the top priority for data center purchasers. Organizations should evaluate their cooling and power needs when selecting between liquid-cooled and air-cooled server nodes.
Further reading
For more on industry infrastructure trends, visit the Data Centers section.
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