Eye Findings Rare in CMV-Positive Infants

A Canadian study found that routine eye exams may be unnecessary for infants who screen positive for congenital cytomegalovirus.

Updated on Oct. 14, 2026 in Babies

Isometric editorial illustration of clinical magnifying lenses on a plain surface, representing diagnostic medical assessment. — A Canadian study suggests that routine ophthalmology exams may not be necessary for infants who are asymptomatic for congenital cytomegalovirus. AI Illustration. Upload story photo >

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Should newborns with no symptoms receive fewer specialty medical referrals to prioritize limited healthcare resources?

A study conducted between July 2019 and January 2022 found that eye abnormalities were rare among infants who tested positive for congenital cytomegalovirus. Researchers determined that routine ophthalmology referrals might not be required for those who are asymptomatic.

Why it matters

Pediatric ophthalmology specialist appointments can be difficult to access in many regions. This study aimed to identify whether a positive screening result alone justifies an urgent referral for all newborns.

The study of 347 infants found that 324 had normal eye examinations, representing 93.4% of the cohort. Only two infants, who both displayed significant signs of disease in other body parts, had chorioretinal scars attributed to the virus.

The players

American Academy of Pediatrics

This professional association of paediatricians provides clinical guidance and health recommendations for the care of infants and children in North America.

The details

Researchers reviewed eye examination data for infants who tested positive for congenital cytomegalovirus, discovering that no asymptomatic infants had CMV-related eye findings. While the American Academy of Pediatrics recommends evaluations for infants showing signs of disease, the findings suggest these scans may not be critical for every patient.

July 2019 to January 2022 served as the study period for reviewing infant eye examination results.

Culture Shift

This research reflects a broader movement in paediatric care toward reducing unnecessary diagnostic testing and specialist referrals for low-risk infants. It highlights a shift in medical practice where clinicians are increasingly balancing evidence-based screenings with the practical realities of overburdened health systems.

Parents of infants who test positive for congenital cytomegalovirus may find that their healthcare providers now have more evidence to avoid unnecessary and potentially stressful specialist referrals. This can reduce the time spent travelling to appointments and alleviate pressure on limited paediatric ophthalmology services in Canada.

The takeaway

This study provides clarity for parents and doctors navigating the results of congenital cytomegalovirus screenings in newborns. It emphasizes that while monitoring is vital for symptomatic children, those without other disease signs may not require immediate ophthalmology intervention.