FMC Corporation Advanced RNA Bioinsecticides to Trials

The company has initiated global field testing for two new RNA-based candidates designed to manage agricultural pests.

Updated on Sept. 27, 2026 in Biotech

Green rows of corn in a large, meticulously managed agricultural test field, viewed from a high angle under clear daylight.
FMC Corporation has initiated global field trials for its new RNA-based bioinsecticides in the United States, Brazil, and Asia to combat lepidopteran pests. AI Illustration. Upload story photo >

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FMC Corporation has moved two RNA-based bioinsecticide candidates into field trials across the United States, Brazil, and Asia. The products aim to combat lepidopteran pests that significantly threaten crop yields.

Why it matters

The development seeks to provide a targeted pest management solution that limits negative effects on beneficial insects. By utilizing specific biological pathways, the technology also offers a potential tool to help farmers manage increasing pest resistance to conventional treatments.

The bioinsecticides use RNA-based biomolecules that target specific biological pathways in pests. AgroSpheres utilizes its AgriCell platform to encapsulate the material, protecting the active ingredients from heat, moisture, and ultraviolet exposure.

The players

FMC Corporation

A Philadelphia-based agricultural sciences company that provides crop protection, plant health, and professional pest and turf management products.

AgroSpheres

A biotechnology company that specializes in the development of encapsulated biological products for agricultural applications.

The details

Developed in collaboration with AgroSpheres, the candidates have already surpassed performance benchmarks in greenhouse and small-scale testing compared to conventional chemistries. The products are designed to target pests such as fall armyworm and diamondback moth through a fermentation-based manufacturing process.

Timeline

  1. FMC and AgroSpheres established their development collaboration in 2024.

  2. Global field trials for the two bioinsecticide candidates began in September 2026.

The Tech Race

This development represents a shift toward precise, RNA-based biologicals that could eventually replace or supplement traditional chemical pesticides. It positions FMC to compete in the growing market for environmentally selective crop protection technologies.

For farmers and the broader agricultural supply chain, this technology promises a new method to maintain crop health while reducing reliance on conventional sprays. If successful, these tools could help stabilize food prices by reducing annual crop losses caused by resistant pests.

The takeaway

These trials represent a significant step in transitioning RNA technology from laboratory settings to commercial field use. The ongoing tests will determine if the candidates can maintain their performance standards across diverse international agricultural environments.

Further reading

Learn more about the latest innovations in the agricultural sector by visiting our Biotech section.

Source note: This article includes information reported by MyChesCo.

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Do you support the rapid expansion of experimental bioinsecticides into global agricultural field trials?