Thermo Scientific Launches DynaChrom Chromatography System
The new chromatography system utilizes closed-loop control to automate and refine purification processes in biotech.
Updated on Sept. 19, 2026 in Biotech
Thermo Scientific has released the DynaChrom Single-Use Chromatography System, a device designed to manage conductivity through model-based control. The system integrates with the TruChrom automation platform to enhance product quality and purification efficiency.
Why it matters
The system aims to improve peak resolution, product recovery, and impurity clearance while reducing manual handling and facility footprint requirements. By optimizing buffer management and storage, it addresses critical operational challenges in bioprocessing.
The system operates across a flow range of 6 to 1,980 L/hr and utilizes model-based, closed-loop control to correct conductivity in real time. Integration with the Emerson DeltaV DCS TruChrom automation platform manages linear and step gradients.
The players
Thermo Scientific
This global company provides analytical instruments, laboratory equipment, and software for the biotechnology and pharmaceutical industries.
Emerson
This technology and engineering company provides automation solutions, including the DeltaV distributed control system used in industrial processes.
The details
The platform employs automated closed-loop technology to minimize overshoot and settling time during chromatography. This design helps users streamline buffer preparation and storage while improving the consistency of product recovery.
Timeline
September 19, 2026: Official details regarding the system were released.
The Tech Race
The DynaChrom system integrates with the Emerson DeltaV DCS, aligning with the industry-wide transition toward fully automated, closed-loop bioprocessing. This move replaces legacy manual chromatography methods with highly precise, model-based control architectures.
Laboratory managers and biotech operators can expect streamlined facility workflows and reduced manual handling of buffer solutions. The system allows users to achieve higher product purity and resolution by minimizing the errors associated with manual conductivity adjustments.
The takeaway
The move toward model-based chromatography reflects a broader shift toward self-correcting automation in pharmaceutical manufacturing. Companies utilizing these systems should prioritize software integration training to maximize the reduction in manual oversight.
Further reading
For more information on the latest innovations in purification technology, visit our Biotech section.
Source note: This article includes information reported by Pharmaceuticalonline.
